Mivavotinib
Diffuse Large B-Cell Lymphoma Activated B-Cell Type
Explore 18 assets in Diffuse Large B-Cell Lymphoma Activated B-Cell Type →Floatz Rating
C33/100
Confidence
Indicative
Sponsor
Northwestern University
Modality
Small molecule
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
18Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03742258CT.gov Combination Chemotherapy and TAK-659 as Front-Line Treatment in Treating Patients With High-Risk Diffuse Large B Cell Lymphoma | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Diffuse Large B-Cell Lymphoma Activated B-Cell Type
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Mivavotinib (this asset) | Northwestern University | P1 | C · 33 |
| Rituximab | Mayo Clinic | P2/3 | B |
| Cyclophosphamide | National Cancer Institute (NCI) | P3 | B |
| Adriamycin | National Cancer Institute (NCI) | P2/3 | B |
| Vincristine Sulfate | National Cancer Institute (NCI) | P2/3 | B |
| Prednisone | National Cancer Institute (NCI) | P2/3 | B |
| Camustine | National Cancer Institute (NCI) | P3 | B |
| Cytarabine | National Cancer Institute (NCI) | P3 | B |
| Melphalan | National Cancer Institute (NCI) | P3 | B |
+12 more in the Diffuse Large B-Cell Lymphoma Activated B-Cell Type cohort
Other indications for Mivavotinib
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Diffuse Large B-Cell Lymphoma | — | P2 | C · 38 |
| Ovarian Carcinoma | — | P1 | C · 33 |
| Refractory Malignant Neoplasm | — | P1 | C · 33 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Mivavotinib in Diffuse Large B-Cell Lymphoma Activated B-Cell Type. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 14, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/mivavotinib-diffuse-large-b-cell-lymphoma-activated-b-cell-type
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