Floatz Rating
D30/100
Confidence
Indicative
Sponsor
MingSight Pharmaceuticals, Inc
Modality
UNKNOWN
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
15Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05720052CT.gov A Study of MS-553 in Patients With Relapsed or Refractory B-cell Lymphoma | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Mantle Cell Lymphoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| ms-553 (this asset) | MingSight Pharmaceuticals, Inc | P1/2 | D · 30 |
| Prednisone | National Cancer Institute (NCI) | P4 | BBB |
| Adriamycin | National Cancer Institute (NCI) | P4 | BBB |
| Etoposide | Ruijin Hospital | P4 | BB |
| Cyclophosphamide | Miltenyi Biomedicine GmbH | P4 | BB |
| Rituximab | City of Hope Medical Center | P4 | BB |
| (+)-Vincristine | National Cancer Institute (NCI) | P4 | BB |
| Cyclosporin A | Fred Hutchinson Cancer Center | P3 | BB |
| Vincristine Sulfate | M.D. Anderson Cancer Center | P2 | BB |
+42 more in the Mantle Cell Lymphoma cohort
Other indications for ms-553
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Lymphoid Leukemia | — | P1/2 | D · 30 |
| B-Cell Non-Hodgkin Lymphoma | — | P1/2 | D · 30 |
| Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | — | P1/2 | D · 30 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. ms-553 in Mantle Cell Lymphoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 14, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ms-553-mantle-cell-lymphoma
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