Murine Autologous Anti-Cd19 Chimeric Antigen Receptor T Cells
Childhood Acute Lymphoblastic Leukemia
Explore 65 assets in Childhood Acute Lymphoblastic Leukemia →Floatz Rating
B57/100
Confidence
Indicative
Sponsor
Beijing Boren Hospital
Modality
Cell therapy
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04325841CT.gov Phase II Study of Anti-CD19 CAR-T Cells Treating Leukemia Children | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Childhood Acute Lymphoblastic Leukemia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Murine Autologous Anti-Cd19 Chimeric Antigen Receptor T Cells (this asset) | Beijing Boren Hospital | P2 | B · 57 |
| Vincristine Sulfate | National Cancer Institute (NCI) | P3 | BBB |
| Cytarabine | Children's Oncology Group | P3 | BBB |
| Cyclophosphamide | St. Jude Children's Research Hospital | P3 | BBB |
| Nivestim | St. Jude Children's Research Hospital | P3 | BBB |
| Mercaptopurine Anhydrous | The Children's Hospital of Zhejiang University School of Medicine | P3 | BBB |
| Pegaspargase | University of Chicago | P3 | BBB |
| Etoposide | Martin Schrappe | P3 | BBB |
| Asparaginase | Therapeutic Advances in Childhood Leukemia Consortium | P3 | BBB |
+42 more in the Childhood Acute Lymphoblastic Leukemia cohort
Other indications for Murine Autologous Anti-Cd19 Chimeric Antigen Receptor T Cells
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Acute Lymphoblastic Leukemia | — | P2 | B · 57 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Murine Autologous Anti-Cd19 Chimeric Antigen Receptor T Cells in Childhood Acute Lymphoblastic Leukemia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/murine-autologous-anti-cd19-chimeric-antigen-receptor-t-cells-childhood-acute-lymphoblastic-leukemia
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