Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Howard S. Hochster, MD
Modality
UNKNOWN
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05296681CT.gov Microbiotic Product to Promote Microbiome Health and Improve Chemotherapy Delivery | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Malignant Colon Neoplasm
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Nbt-Nm108 (this asset) | Howard S. Hochster, MD | P2 | CCC · 53 |
| Tranexamic Acid | Assaf-Harofeh Medical Center | P4 | BB |
| Fluorouracilum | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | P2 | BB |
| Regorafenib | City of Hope Medical Center | P2 | B |
| Oxaliplatin | Second Affiliated Hospital, School of Medicine, Zhejiang University | P2 | B |
| Irinotecan | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | P2 | B |
| Cetuximab | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | P2 | B |
| Celecoxib | Tel-Aviv Sourasky Medical Center | P3 | B |
| Nivolumab | M.D. Anderson Cancer Center | P1/2 | B |
+26 more in the Malignant Colon Neoplasm cohort
Other indications for Nbt-Nm108
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Prader-Willi Syndrome | — | P2 | B · 57 |
| Colon Carcinoma | — | P2 | CCC · 53 |
| Obesity Disorder | — | P2 | CCC · 48 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- Tranexamic AcidAssaf-Harofeh Medical CenterBB
- FluorouracilumFondazione Policlinico Universitario Agostino Gemelli IRCCSBB
- RegorafenibCity of Hope Medical CenterB
- OxaliplatinSecond Affiliated Hospital, School of Medicine, Zhejiang UniversityB
- IrinotecanFondazione Policlinico Universitario Agostino Gemelli IRCCSB
Citation
Floatz Terminal. Nbt-Nm108 in Malignant Colon Neoplasm. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/nbt-nm108-malignant-colon-neoplasm
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