Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
M.D. Anderson Cancer Center
Modality
mixture
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04729322CT.gov Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Small Intestine Adenocarcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Neomycin (this asset) | M.D. Anderson Cancer Center | P2 | CCC · 53 |
| Dostarlimab | UNICANCER | P2 | CCC |
| Human Adenovirus C Serotype 5 | Thomas Jefferson University | P2 | CCC |
| Adenovirus 5/F35-Human Guanylyl Cyclase C-Padre | Thomas Jefferson University | P2 | CCC |
| Vancomycin | M.D. Anderson Cancer Center | P2 | CCC |
| Pembrolizumab | M.D. Anderson Cancer Center | P2 | CCC |
| Nivolumab | M.D. Anderson Cancer Center | P2 | CCC |
| Vandazole | M.D. Anderson Cancer Center | P2 | CCC |
| Ipilimumab | National Cancer Institute (NCI) | P2 | CCC |
+15 more in the Small Intestine Adenocarcinoma cohort
Other indications for Neomycin
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Rectal Carcinoma | — | P4 | B · 63 |
| Colorectal Neoplasm | — | P4 | B · 63 |
| Colorectal Cancer | — | P4 | B · 58 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Neomycin in Small Intestine Adenocarcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/neomycin-small-intestine-adenocarcinoma
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