Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Instituto Nacional de Cancer, Brazil
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05800834CT.gov Benefits of Morphine Gel for Pain Reduction in Patients With Cancer Wounds | — | Unknown | — | — | — |
NCT05355441CT.gov Pain Multidisciplinar Intervention in Major Trauma Patients | — | Completed | — | — | — |
NCT00306020CT.gov Analgesia and Wound Healing Assessment Following Topical Morphine Applied to Patients With Cutaneous Cancer Related Pain | — | Withdrawn | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Injury
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Nepenthe (this asset) | Instituto Nacional de Cancer, Brazil | P2 | CCC · 53 |
| Testosterone Undecylate | Craig Hospital | P4 | BB |
| Tranexamic Acid | Daniel Nishijima, MD, MAS | P3 | BB |
| Glucose, Anhydrous | Baskent University | P4 | BB |
| Apsolol | Hamad Medical Corporation | P4 | BB |
| Midazolam | Baskent University | P4 | BB |
| Conestat Alfa | UMC Utrecht | P3 | B |
| Epoetin Alfa | Australian and New Zealand Intensive Care Research Centre | P3 | B |
| Eptacog Alfa (Activated) | Novo Nordisk A/S | P2 | B |
+21 more in the Injury cohort
Other indications for Nepenthe
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Cancer Of Unknown Primary Site | — | P4 | BBB · 75 |
| Chronic Pain Syndrome | — | P4 | BBB · 74 |
| Post-Operative Pain, Non-Human Animal | — | P4 | BBB · 73 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Nepenthe in Injury. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/nepenthe-injury
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