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Floatz Rating
B59/100
Confidence
Indicative
v0.2
Sponsor
National University Hospital, Singapore
Modality
monoclonal_antibody
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
51High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers
Recruiting
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
Recruiting
Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies
Recruiting
A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer
Completed
A Study of Emibetuzumab in Combination With Ramucirumab (LY3009806) in Participants With Advanced Cancer
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
73High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Gastric Adenocarcinoma

AssetSponsorPhaseRating
Nivolumab (this asset)National University Hospital, SingaporeP2B · 59
FluorouracilumBoehringer IngelheimP3BB
TrastuzumabBoehringer IngelheimP2BB
CapecitabineShanghai Zhongshan HospitalP3BB
Cis-Diamminedichloroplatinum IiMayo ClinicP3BB
OxaliplatinShanghai Zhongshan HospitalP3BB
PembrolizumabEpkinP3BB
DurvalumabUniversity of California, IrvineP2B
IrinotecanGeorgetown UniversityP3B

+42 more in the Gastric Adenocarcinoma cohort

Other indications for Nivolumab

IndicationSponsorPhaseRating
Renal CarcinomaP4BBB · 72
Metastatic MelanomaP4BB · 70
Non-Small Cell Lung CarcinomaP4BB · 70

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Nivolumab in Gastric Adenocarcinoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/nivolumab-gastric-adenocarcinoma

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