Floatz Rating
B57/100
Confidence
Indicative
Sponsor
Novo Nordisk A/S
Modality
UNKNOWN
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
45Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07567001CT.gov A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity | — | Not Yet Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Heart Failure
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| nnc0487-0111 (this asset) | Novo Nordisk A/S | P3 | B · 57 |
| Empagliflozin | Jacob Moller | P4 | BB |
| Finerenone | Hospital de Messejana Dr. Carlos Alberto Studart Gomes | P4 | BB |
| Semaglutide | University Medical Centre Ljubljana | P2/3 | BB |
| Carvedilol | Abramson Cancer Center at Penn Medicine | P3 | BB |
| Rivaroxaban | Janssen Research & Development, LLC | P3 | B |
| Acalabrutinib | AstraZeneca | P4 | B |
| Sacubitril Valsartan | Silesian Centre for Heart Diseases | P4 | B |
| Spironolactone | Hospital de Messejana Dr. Carlos Alberto Studart Gomes | P4 | B |
+32 more in the Heart Failure cohort
Other indications for nnc0487-0111
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Type 2 Diabetes Mellitus | — | P3 | B · 62 |
| Obstructive Sleep Apnea Syndrome | — | P3 | B · 60 |
| Diabetes Mellitus | — | P3 | B · 60 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. nnc0487-0111 in Heart Failure. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/nnc0487-0111-heart-failure
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