Floatz Rating
BB64/100
Confidence
Indicative
Sponsor
City of Hope Medical Center
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
49High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00002515CT.gov Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Extragonadal Germ Cell Tumor
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Nogitecan (this asset) | City of Hope Medical Center | P2 | BB · 64 |
| Nivestim | City of Hope Medical Center | P2 | BBB |
| Etoposide | City of Hope Medical Center | P3 | BBB |
| Carboplatin | City of Hope Medical Center | P3 | BB |
| Cis-Diamminedichloroplatinum Ii | Memorial Sloan Kettering Cancer Center | P3 | BB |
| Cyclophosphamide | UNICANCER | P2 | BB |
| Isocyclophosphamide | City of Hope Medical Center | P3 | BB |
| Bleomycin | Children's Cancer and Leukaemia Group | P3 | BB |
| L-Ofloxacin | Cancer Research Campaign Clinical Trials Centre | P3 | BB |
+26 more in the Extragonadal Germ Cell Tumor cohort
Other indications for Nogitecan
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Primary Peritoneal Carcinoma | — | P3 | BBB · 74 |
| Cancer Of Unknown Primary Site | — | P2 | BBB · 72 |
| Non-Small Cell Lung Carcinoma | — | P3 | BBB · 72 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Nogitecan in Extragonadal Germ Cell Tumor. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/nogitecan-extragonadal-germ-cell-tumor
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