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Obicetrapib

Type 2 Diabetes Mellitus

Explore 135 assets in Type 2 Diabetes Mellitus
Floatz Rating
B60/100
Confidence
Indicative
v0.2
Sponsor
NewAmsterdam Pharma
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
45Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89Moderate confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Type 2 Diabetes Mellitus

AssetSponsorPhaseRating
Obicetrapib (this asset)NewAmsterdam PharmaP3B · 60
LiraglutideRenJi HospitalP4BBB
DapagliflozinBhavya Bhavya, MDP4BBB
CotadutideAstraZenecaP2BBB
SemaglutideShanghai Jiao Tong University School of MedicineP4BBB
ExenatideVivani Medical, IncP4BBB
MetforminMyopharm LimitedP4BBB
SaxagliptinNick Giannoukakis, PhDP4BBB
PioglitazoneSeoul National University Bundang HospitalP4BBB

+41 more in the Type 2 Diabetes Mellitus cohort

Other indications for Obicetrapib

IndicationSponsorPhaseRating
HyperlipidemiaP3B · 60
Alzheimer DiseaseP2B · 57

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Obicetrapib in Type 2 Diabetes Mellitus. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/obicetrapib-type-2-diabetes-mellitus

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