Omega-N-Methylarginine
Metaplastic Breast Carcinoma
Explore 3 assets in Metaplastic Breast Carcinoma →Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
The Methodist Hospital Research Institute
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05660083CT.gov Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC) | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Metaplastic Breast Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Omega-N-Methylarginine (this asset) | The Methodist Hospital Research Institute | P2 | CCC · 53 |
| Nivolumab | Instituto do Cancer do Estado de São Paulo | P2 | CCC |
| Ipilimumab | National Cancer Institute (NCI) | P2 | CCC |
Other indications for Omega-N-Methylarginine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Sickle Cell Disease | — | P2 | BB · 67 |
| Triple-Negative Breast Carcinoma | — | P2 | BB · 64 |
| Obesity Disorder | — | P4 | B · 60 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Omega-N-Methylarginine in Metaplastic Breast Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/omega-n-methylarginine-metaplastic-breast-carcinoma
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