Floatz Rating
BB64/100
Confidence
Indicative
Sponsor
Member Companies of the Opioid PMR Consortium
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
49Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02741076CT.gov Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Substance Abuse
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Oxycodone (this asset) | Member Companies of the Opioid PMR Consortium | Approved | BB · 64 |
| Quetiapine | Boston Medical Center | P4 | BBB |
| Risperidone | Dartmouth-Hitchcock Medical Center | P4 | BBB |
| 17.BETA.-(1-KETOETHYL)-.DELTA. SUP(5)-ANDROSTEN-3.BETA.-OL | University of Texas Southwestern Medical Center | P4 | BB |
| Brexpiprazole | University of Massachusetts, Worcester | P4 | BB |
| Olanzapine | Augusta University | P4 | BB |
| Clozapine | Augusta University | P4 | BB |
| Valproic Acid | Creighton University | P4 | BB |
| Paliperidone | The University of Hong Kong | P2/3 | B |
+18 more in the Substance Abuse cohort
Other indications for Oxycodone
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Vertebral Column Disorder | — | P4 | BBB · 73 |
| Osteoarthritis | — | P4 | BBB · 73 |
| Chronic Pain Syndrome | — | P4 | BBB · 73 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Oxycodone in Substance Abuse. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/oxycodone-substance-abuse
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