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Palbociclib

Hormone-Resistant Breast Carcinoma

Explore 4 assets in Hormone-Resistant Breast Carcinoma
Floatz Rating
D30/100
Confidence
Indicative
v0.2
Sponsor
Fudan University
Modality
Small molecule
Development Phase
N/A
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
15Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast Cancer
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Hormone-Resistant Breast Carcinoma

AssetSponsorPhaseRating
Palbociclib (this asset)Fudan UniversityN/AD · 30
GanetespibSynta Pharmaceuticals Corp.P2CCC
trx518Leap Therapeutics, Inc.P1CC
ag-01 compoundA&G Pharmaceutical Inc.P1CC
CyclophosphamideLeap Therapeutics, Inc.P1CC
AvelumabLeap Therapeutics, Inc.P1CC
FulvestrantFudan UniversityN/AD
SirolimusFudan UniversityN/AD

Other indications for Palbociclib

IndicationSponsorPhaseRating
Her2-Receptor Negative Breast CancerP2BBB · 75
Hormone Receptor-Positive Breast CancerP3BBB · 73
Breast CancerP4BB · 71

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Palbociclib in Hormone-Resistant Breast Carcinoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/palbociclib-hormone-resistant-breast-carcinoma

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