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Palbociclib

MIT Family Translocation Renal Cell Carcinoma

Explore 8 assets in MIT Family Translocation Renal Cell Carcinoma
Floatz Rating
CCC53/100
Confidence
Indicative
v0.2
Sponsor
Stephanie Berg
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · MIT Family Translocation Renal Cell Carcinoma

AssetSponsorPhaseRating
Palbociclib (this asset)Stephanie BergP2CCC · 53
CabozantinibMemorial Sloan Kettering Cancer CenterP2B
IpilimumabBradley A. McGregor, MDP2CCC
AxitinibStephanie BergP2CCC
NivolumabInstituto do Cancer do Estado de São PauloP2CCC
AbemaciclibMemorial Sloan Kettering Cancer CenterP1/2CC
Cytokine Induced Memory-Like Natural Killer CellsDana-Farber Cancer InstituteEarly P1C
SasanlimabStephanie BergP2C

Other indications for Palbociclib

IndicationSponsorPhaseRating
Her2-Receptor Negative Breast CancerP2BBB · 75
Hormone Receptor-Positive Breast CancerP3BBB · 73
Breast CancerP4BB · 71

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Palbociclib in MIT Family Translocation Renal Cell Carcinoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/palbociclib-mit-family-translocation-renal-cell-carcinoma

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