Pan-Fgfr Tyrosine Kinase Inhibitor Jnj-42756493
Prostate Small Cell Carcinoma
Explore 20 assets in Prostate Small Cell Carcinoma →Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
M.D. Anderson Cancer Center
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04754425CT.gov Erdafitinib for the Treatment of Patients With Castration-Resistant Prostate Cancer | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Prostate Small Cell Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Pan-Fgfr Tyrosine Kinase Inhibitor Jnj-42756493 (this asset) | M.D. Anderson Cancer Center | P2 | CCC · 53 |
| Carboplatin | M.D. Anderson Cancer Center | P2 | BB |
| Prednisone | Fred Hutchinson Cancer Center | P2 | B |
| Cabazitaxel | M.D. Anderson Cancer Center | P2 | B |
| Pembrolizumab | Rahul Aggarwal | P2 | B |
| Alisertib | Weill Medical College of Cornell University | P2 | B |
| Cetrelimab | Rahul Aggarwal | P2 | CCC |
| Cabozantinib | National Cancer Institute (NCI) | P2 | CCC |
| Oxodotreotide | National Cancer Institute (NCI) | P2 | CCC |
+14 more in the Prostate Small Cell Carcinoma cohort
Other indications for Pan-Fgfr Tyrosine Kinase Inhibitor Jnj-42756493
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Neoplasm | — | P2 | B · 60 |
| Bladder Transitional Cell Carcinoma | — | P2 | B · 58 |
| Hepatocellular Carcinoma | — | P2 | B · 58 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Pan-Fgfr Tyrosine Kinase Inhibitor Jnj-42756493 in Prostate Small Cell Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/pan-fgfr-tyrosine-kinase-inhibitor-jnj-42756493-prostate-small-cell-carcinoma
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