Floatz Rating
B56/100
Confidence
Indicative
Sponsor
M.D. Anderson Cancer Center
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
41Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02506959CT.gov Panobinostat, Gemcitabine Hydrochloride, Busulfan, and Melphalan Before Stem Cell Transplant in Treating Patients With Refractory or Relapsed Multiple Myeloma | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Plasmacytoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Panobinostat (this asset) | M.D. Anderson Cancer Center | P2 | B · 56 |
| Dexasone | Memorial Sloan Kettering Cancer Center | P2 | B |
| Lenalidomide | Memorial Sloan Kettering Cancer Center | P2 | B |
| Melphalan | M.D. Anderson Cancer Center | P2 | B |
| Pomalidomide | Mayo Clinic | P2 | B |
| Busulfanum | M.D. Anderson Cancer Center | P2 | B |
| Azacitidine | Memorial Sloan Kettering Cancer Center | P2 | CCC |
| Milatuzumab | Gilead Sciences | P1/2 | CCC |
| Bcma-Cart Cells | Institute of Hematology & Blood Diseases Hospital, China | P1/2 | CCC |
+4 more in the Plasmacytoma cohort
Other indications for Panobinostat
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Hodgkins Lymphoma | — | P3 | BB · 68 |
| Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | — | P2 | BB · 66 |
| Mantle Cell Lymphoma | — | P2 | BB · 66 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Panobinostat in Plasmacytoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/panobinostat-plasmacytoma
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