Patient Derived Cd19 Specific Car T Cells Also Expressing An Egfrt
Acute Leukemia
Explore 60 assets in Acute Leukemia →Floatz Rating
CCC48/100
Confidence
Indicative
Sponsor
Seattle Children's Hospital
Modality
Cell therapy
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02028455CT.gov A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD19 for Relapsed/Refractory CD19+ Leukemia | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Acute Leukemia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Patient Derived Cd19 Specific Car T Cells Also Expressing An Egfrt (this asset) | Seattle Children's Hospital | P1/2 | CCC · 48 |
| Fludarabine | Sawa Ito, MD | P2/3 | BB |
| Cyclophosphamide | Sawa Ito, MD | P4 | BB |
| Cytarabine | Janssen Research & Development, LLC | P2/3 | BB |
| Busulfanum | Sawa Ito, MD | P4 | BB |
| Adriamycin | SWOG Cancer Research Network | P2/3 | BB |
| Etoposide | SWOG Cancer Research Network | P2/3 | BB |
| Tacrolimus | Masonic Cancer Center, University of Minnesota | P3 | BB |
| Methotrexate | SWOG Cancer Research Network | P3 | BB |
+42 more in the Acute Leukemia cohort
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Patient Derived Cd19 Specific Car T Cells Also Expressing An Egfrt in Acute Leukemia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/patient-derived-cd19-specific-car-t-cells-also-expressing-an-egfrt-acute-leukemia
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