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Floatz Rating
D30/100
Confidence
Indicative
v0.2
Sponsor
Universitaire Ziekenhuizen KU Leuven
Modality
Small molecule
Development Phase
N/A
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
15Moderate confidence
Detailed axis rationale is planned and will be published soon.

No trial-level evidence is linked to this axis yet.

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Psychotic Disorder

AssetSponsorPhaseRating
PE 2I (this asset)Universitaire Ziekenhuizen KU LeuvenN/AD · 30
OlanzapineShanghai Jiao Tong University School of MedicineP4BBB
RisperidoneNorthwell HealthP4BBB
PaliperidoneConsorcio Centro de Investigación Biomédica en Red (CIBER)P4BBB
AsenapineCentre de Recherche de l'Institut Universitaire en Santé Mentale de QuébecP4BBB
EukystolFundación Pública Andaluza para la gestión de la Investigación en SevillaP4BBB
SimvastatinMclean HospitalP4BBB
SertralineNorthwell HealthP4BBB
QuetiapineShanghai Jiao Tong University School of MedicineP4BBB

+42 more in the Psychotic Disorder cohort

Other indications for PE 2I

IndicationSponsorPhaseRating
REM Sleep Behavior DisorderP1/2CCC · 52
Parkinson DiseaseP1/2CC · 44
Alzheimer DiseaseN/AD · 30

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. PE 2I in Psychotic Disorder. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/pe-2i-psychotic-disorder

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