Pegaspargase
Mature T-Cell And NK-Cell Non-Hodgkin Lymphoma
Explore 36 assets in Mature T-Cell And NK-Cell Non-Hodgkin Lymphoma →Floatz Rating
BB65/100
Confidence
Indicative
Sponsor
Zhengzhou University
Modality
protein_peptide
Development Phase
Phase 4 / Approved
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
55Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04999878CT.gov A Prospective Clinical Study of Ruxolitinib and Etoposide Combined With DDGP Regimen (RUE-DDGP) in Induction Therapy of T/NK Cell Lymphoma-associated Hemophagocytic Syndrome. | — | Unknown | — | — | — |
NCT01403415CT.gov Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Mature T-Cell And NK-Cell Non-Hodgkin Lymphoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Pegaspargase (this asset) | Zhengzhou University | Approved | BB · 65 |
| Etoposide | Alliance for Clinical Trials in Oncology | P4 | BB |
| Cyclophosphamide | City of Hope Medical Center | P2 | BB |
| Dexasone | Zhengzhou University | P4 | BB |
| Nivestim | City of Hope Medical Center | P2 | BB |
| Prednisone | City of Hope Medical Center | P2 | BB |
| (+)-Vincristine | City of Hope Medical Center | P2 | BB |
| Adriamycin | City of Hope Medical Center | P2 | BB |
| Romidepsin | Walter Hanel | P2 | BB |
+42 more in the Mature T-Cell And NK-Cell Non-Hodgkin Lymphoma cohort
Other indications for Pegaspargase
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| B-Cell Childhood Acute Lymphoblastic Leukemia | — | P3 | A · 80 |
| Extranodal Nasal NK/T Cell Lymphoma | — | P4 | BBB · 76 |
| Non-Hodgkin Lymphoma | — | P4 | BBB · 75 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Pegaspargase in Mature T-Cell And NK-Cell Non-Hodgkin Lymphoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/pegaspargase-mature-t-cell-and-nk-cell-non-hodgkin-lymphoma
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