Pembrolizumab
Testicular Non-Seminomatous Germ Cell Tumor
Explore 4 assets in Testicular Non-Seminomatous Germ Cell Tumor →Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Nasser Hanna, M.D.
Modality
monoclonal_antibody
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02499952CT.gov Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell Tumors | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Testicular Non-Seminomatous Germ Cell Tumor
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Pembrolizumab (this asset) | Nasser Hanna, M.D. | P2 | CCC · 53 |
| Palbociclib | Abramson Cancer Center at Penn Medicine | P2 | B |
| Etoposide | Nabil Adra | P2 | CCC |
| Ipilimumab | National Cancer Institute (NCI) | P2 | CCC |
| Nivolumab | National Cancer Institute (NCI) | P2 | CCC |
| Cabozantinib | Jennifer King | P2 | CCC |
| Nogitecan | City of Hope Medical Center | P1 | CC |
| Nivestim | City of Hope Medical Center | P1 | CC |
| Melphalan | City of Hope Medical Center | P1 | CC |
+1 more in the Testicular Non-Seminomatous Germ Cell Tumor cohort
Other indications for Pembrolizumab
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Her2-Receptor Negative Breast Cancer | — | P2 | BBB · 72 |
| Estrogen-Receptor Negative Breast Cancer | — | P2 | BB · 71 |
| Progesterone-Receptor Negative Breast Cancer | — | P2 | BB · 71 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Pembrolizumab in Testicular Non-Seminomatous Germ Cell Tumor. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/pembrolizumab-testicular-non-seminomatous-germ-cell-tumor
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