Petadeferitrin
Iron Metabolism Disease
Floatz Rating
CCC50/100
Confidence
Indicative
Sponsor
Abfero Pharmaceuticals, Inc
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
35Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03801889CT.gov SP-420 in Subjects With Transfusion-dependent Beta-Thalassemia or Other Rare Anemias | — | Withdrawn | — | — | — |
NCT02274233CT.gov Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Iron Metabolism Disease
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Petadeferitrin (this asset) | Abfero Pharmaceuticals, Inc | P2 | CCC · 50 |
| Deferasirox | Kevin H.M. Kuo, MD, MSc, FRCPC | P4 | BBB |
| Desferrioxamine B | Beni-Suef University | P4 | BBB |
| Deferiprone | Chiesi Canada Corp | P4 | BBB |
| Amlodipine | Kevin H.M. Kuo, MD, MSc, FRCPC | P3 | BB |
| Hydroxyurea | Beni-Suef University | P2/3 | B |
| Nigella Sativa Oil | Beni-Suef University | P2/3 | B |
| Silymarin | Isfahan University of Medical Sciences | P2/3 | B |
| Deferitazole | Shire | P2 | CCC |
+3 more in the Iron Metabolism Disease cohort
Other indications for Petadeferitrin
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Beta Thalassemia | — | P2 | CCC · 50 |
| Beta-Thalassemia Major | — | P2 | CC · 46 |
| Myelodysplastic Syndrome | — | P2 | CC · 46 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Petadeferitrin in Iron Metabolism Disease. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/petadeferitrin-iron-metabolism-disease
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