Polatuzumab Vedotin
Post-Transplant Lymphoproliferative Disease
Explore 17 assets in Post-Transplant Lymphoproliferative Disease →Floatz Rating
CC47/100
Confidence
Indicative
Sponsor
Washington University School of Medicine
Modality
antibody_drug_conjugate
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06040320CT.gov Polatuzumab Vedotin (Pola) Plus Rituximab (R) in Patients With Post-transplant Lymphoproliferative Disorder (PTLD) | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Post-Transplant Lymphoproliferative Disease
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Polatuzumab Vedotin (this asset) | Washington University School of Medicine | P1/2 | CC · 47 |
| Cyclophosphamide | Washington University School of Medicine | P2 | BBB |
| Rituximab | Jennifer Amengual | P2 | BB |
| Fludarabine | City of Hope Medical Center | P2 | BB |
| Cyclosporin A | National Cancer Institute (NCI) | P2 | BB |
| Lenalidomide | Northwestern University | P2 | B |
| Nivestim | Baylor College of Medicine | P2 | B |
| Methotrexate | National Cancer Institute (NCI) | P2 | B |
| Tacrolimus | University of Medicine and Dentistry of New Jersey | P2 | B |
+39 more in the Post-Transplant Lymphoproliferative Disease cohort
Other indications for Polatuzumab Vedotin
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Diffuse Large B-Cell Lymphoma | — | P3 | BB · 69 |
| Non-Hodgkin Lymphoma | — | P3 | BB · 65 |
| Relapsed/Refractory Diffuse Large B-Cell Lymphoma | — | P3 | BB · 64 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Polatuzumab Vedotin in Post-Transplant Lymphoproliferative Disease. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/polatuzumab-vedotin-post-transplant-lymphoproliferative-disease
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