Polyethyleneglycol-7-Ethyl-10-Hydroxycamptothecin Dfp-13318
Breast Disorder
Explore 24 assets in Breast Disorder →Floatz Rating
CCC50/100
Confidence
Indicative
Sponsor
Institut Curie
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
35Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06162351CT.gov A Study to Evaluate the Efficacy and Toxicities of PLX038, in Patients With Locally Advanced or Metastatic Triple-negative Breast Cancer | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Breast Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Polyethyleneglycol-7-Ethyl-10-Hydroxycamptothecin Dfp-13318 (this asset) | Institut Curie | P2 | CCC · 50 |
| Trastuzumab | Incepta Pharmaceuticals Ltd | P3 | BB |
| Sacubitril Valsartan | Silesian Centre for Heart Diseases | P4 | BB |
| Vinorelbine Ditartrate | Sun Yat-sen University | P2 | BB |
| Olaparib | AstraZeneca | P2 | BB |
| Capecitabine | University of Southern California | P3 | B |
| Tamoxifen | Fujian Cancer Hospital | P2/3 | B |
| Letrozole | Fujian Cancer Hospital | P2/3 | B |
| Anastrozole | Fujian Cancer Hospital | P2 | B |
+37 more in the Breast Disorder cohort
Other indications for Polyethyleneglycol-7-Ethyl-10-Hydroxycamptothecin Dfp-13318
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Ovarian Carcinoma | — | P2 | CCC · 50 |
| Primary Peritoneal Carcinoma | — | P2 | CCC · 50 |
| Fallopian Tube Cancer | — | P2 | CCC · 50 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Polyethyleneglycol-7-Ethyl-10-Hydroxycamptothecin Dfp-13318 in Breast Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/polyethyleneglycol-7-ethyl-10-hydroxycamptothecin-dfp-13318-breast-disorder
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