Poly((N-(2-Hydroxypropyl)Methacrylamide)-Co-(Methacryloyl-Gly-Phe-Leu-Gly Amide With O-((Trans-4-Aminocyclohexyl)Carbamoyl)Fumagillol)) (~0.91:0.09 X)
Breast Cancer
Explore 849 assets in Breast Cancer →Floatz Rating
CCC50/100
Confidence
Indicative
Sponsor
Memorial Sloan Kettering Cancer Center
Modality
Other
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
45Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05570253CT.gov A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer | — | Recruiting | — | — | — |
NCT05455619CT.gov Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
59High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Breast Cancer
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Poly((N-(2-Hydroxypropyl)Methacrylamide)-Co-(Methacryloyl-Gly-Phe-Leu-Gly Amide With O-((Trans-4-Aminocyclohexyl)Carbamoyl)Fumagillol)) (~0.91:0.09 X) (this asset) | Memorial Sloan Kettering Cancer Center | P2 | CCC · 50 |
| Darolutamide | Vandana Abramson | P2 | BBB |
| Pertuzumab | SWOG Cancer Research Network | P4 | BB |
| Palbociclib | Hoffmann-La Roche | P4 | BB |
| Trastuzumab Duocarmazine | Byondis B.V. | P3 | BB |
| Goserelin | TerSera Therapeutics LLC | P4 | BB |
| Ribociclib | National Cancer Institute (NCI) | P4 | BB |
| Oxaliplatin | Beijing Biostar Pharmaceuticals Co., Ltd. | P4 | BB |
| Eribulin Monomethanesulfonate | Henan Cancer Hospital | P4 | BB |
+42 more in the Breast Cancer cohort
Other indications for Poly((N-(2-Hydroxypropyl)Methacrylamide)-Co-(Methacryloyl-Gly-Phe-Leu-Gly Amide With O-((Trans-4-Aminocyclohexyl)Carbamoyl)Fumagillol)) (~0.91:0.09 X)
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Triple-Negative Breast Carcinoma | — | P2 | CCC · 53 |
| Cancer | — | P1 | CC · 46 |
| Neoplasm | — | P1 | CC · 46 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Poly((N-(2-Hydroxypropyl)Methacrylamide)-Co-(Methacryloyl-Gly-Phe-Leu-Gly Amide With O-((Trans-4-Aminocyclohexyl)Carbamoyl)Fumagillol)) (~0.91:0.09 X) in Breast Cancer. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/polyn-2-hydroxypropylmethacrylamide-co-methacryloyl-gly-phe-leu-gly-amide-with-o-trans-4-aminocyclohexylcarbamoylfumagillol-091009-x-breast-cancer
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