Floatz Rating
B63/100
Confidence
Indicative
Sponsor
BHR Pharma, LLC
Modality
Small molecule
Development Phase
Phase 3
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
48Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT01143064CT.gov Efficacy and Safety Study of Intravenous Progesterone in Patients With Severe Traumatic Brain Injury | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Brain Injury
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Progesterone (this asset) | BHR Pharma, LLC | P3 | B · 63 |
| Apsolol | Hamad Medical Corporation | P4 | BB |
| Tranexamic Acid | Daniel Nishijima, MD, MAS | P3 | BB |
| Testosterone Undecylate | Craig Hospital | P4 | BB |
| Enoxaparin | Hennepin Healthcare Research Institute | P4 | BB |
| Methylphenidate | Dartmouth-Hitchcock Medical Center | P4 | BB |
| Serostim | Pfizer | P4 | BB |
| Trofinetide | Neuren Pharmaceuticals Limited | P2 | B |
| Botulinum B Toxin | Georgetown University | P4 | B |
+40 more in the Brain Injury cohort
Other indications for Progesterone
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Polycystic Ovary Syndrome | — | P4 | BB · 71 |
| Traumatic Brain Injury | — | P4 | BB · 67 |
| Infertility Disorder | — | P4 | BB · 66 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Progesterone in Brain Injury. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/progesterone-brain-injury
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