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Floatz Rating
CC42/100
Confidence
Indicative
v0.2
Sponsor
Prelude Therapeutics
Modality
UNKNOWN
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
31Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Study of PRT1419 in Patients With Advanced Solid Tumors
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
73High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Sarcoma

AssetSponsorPhaseRating
PRT1419 (this asset)Prelude TherapeuticsP1CC · 42
EtoposideNational Cancer Institute (NCI)P2BB
CyclophosphamideEssen BiotechP2BB
IsocyclophosphamideCity of Hope Medical CenterP3BB
CarboplatinOHSU Knight Cancer InstituteP2BB
AdriamycinCity of Hope Medical CenterP3BB
Cis-Diamminedichloroplatinum IiRoswell Park Cancer InstituteP2BB
NivestimMasonic Cancer Center, University of MinnesotaP3BB
Sodium ThiosulfateMayo ClinicP3BB

+42 more in the Sarcoma cohort

Other indications for PRT1419

IndicationSponsorPhaseRating
Head And Neck CancerP1CC · 42
Non-Hodgkin LymphomaP1CC · 42
Myeloproliferative NeoplasmP1CC · 41

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. PRT1419 in Sarcoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/prt1419-sarcoma

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