Floatz Rating
CCC52/100
Confidence
Indicative
Sponsor
University of Wisconsin, Madison
Modality
vaccine
Development Phase
Phase 1/2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
37Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02499835CT.gov Vaccine Therapy and Pembrolizumab in Treating Patients With Hormone-Resistant, Metastatic Prostate Cancer | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Metastatic Carcinoma In The Bone
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Ptvg-Hp (this asset) | University of Wisconsin, Madison | P1/2 | CCC · 52 |
| Denosumab | Kelly Fitzgerald, MD | P4 | BBB |
| Zoledronate | Kelly Fitzgerald, MD | P4 | BBB |
| Ibandronate | Kelly Fitzgerald, MD | P4 | BBB |
| Radium Ra-223 | University of California, San Francisco | P3 | BB |
| Zometa | Sun Yat-sen University | P4 | BB |
| Technetium Tc-99M Cation, Unspecified | University of California, San Francisco | P3 | BB |
| Dentalfluoro | HTA Co., Ltd. | P3 | BB |
| Cabozantinib | National Cancer Institute (NCI) | P3 | BB |
+42 more in the Metastatic Carcinoma In The Bone cohort
Other indications for Ptvg-Hp
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Prostate Cancer | — | P2 | B · 63 |
| Castration-Resistant Prostate Carcinoma | — | P2 | CCC · 53 |
| Hormone-Resistant Prostate Carcinoma | — | P1/2 | CCC · 52 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Ptvg-Hp in Metastatic Carcinoma In The Bone. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ptvg-hp-metastatic-carcinoma-in-the-bone
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