Floatz Rating
CC46/100
Confidence
Indicative
Sponsor
Parvus Therapeutics, Inc.
Modality
UNKNOWN
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06798454CT.gov Single Ascending Dose Study to Evaluate Safety Tolerability, Pharmacokinetics, and Pharmacodynamics of PVT201 in Healthy Subjects and Patients (PBC/PSC) | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Primary Biliary Cholangitis
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| pvt201 (this asset) | Parvus Therapeutics, Inc. | P1 | CC · 46 |
| Ursodeoxycholic Acid | Xijing Hospital of Digestive Diseases | P4 | A |
| Saroglitazar | Zydus Therapeutics Inc. | P3 | BB |
| Fenofibrate | Xijing Hospital of Digestive Diseases | P3 | BB |
| cs0159 | Cascade Pharmaceuticals, Inc | P3 | BB |
| Obeticholic Acid | Intercept Pharmaceuticals | P3 | BB |
| Seladelpar | Gilead Sciences | P3 | BB |
| 2-(P-(2-(P-CHLOROBENZAMIDO)ETHYL)PHENOXY)-2-METHYLPROPIONIC ACID | Intercept Pharmaceuticals | P3 | BB |
| Abatacept Recombinant | Christopher Bowlus, MD | P4 | BB |
+41 more in the Primary Biliary Cholangitis cohort
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. pvt201 in Primary Biliary Cholangitis. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/pvt201-primary-biliary-cholangitis
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