Floatz Rating
CC47/100
Confidence
Indicative
Sponsor
Fred Hutchinson Cancer Center
Modality
Small molecule
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
No trial-level evidence is linked to this axis yet.
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Malignant Renal Pelvis Neoplasm
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Quemliclustat (this asset) | Fred Hutchinson Cancer Center | P1/2 | CC · 47 |
| Enfortumab Vedotin (Fully Human Monoclonal Antibody Conjugated To A Cytotoxic Agent Monomethyl Auristatin E (Mmae) Targeting Nectin-4) | Fred Hutchinson Cancer Center | P2 | BB |
| Pembrolizumab | Fred Hutchinson Cancer Center | P2 | B |
| Atezolizumab | National Cancer Institute (NCI) | P2 | B |
| Apsolol | Emory University | P2 | CCC |
| Eribulin Monomethanesulfonate | National Cancer Institute (NCI) | P2 | CCC |
| Relatlimab | M.D. Anderson Cancer Center | P2 | CCC |
| Nivolumab | M.D. Anderson Cancer Center | P2 | CCC |
| Tocilizumab | M.D. Anderson Cancer Center | P2 | CCC |
+6 more in the Malignant Renal Pelvis Neoplasm cohort
Other indications for Quemliclustat
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Pancreatic Ductal Adenocarcinoma | — | P3 | B · 57 |
| Metastatic Prostate Carcinoma | — | P2 | CCC · 53 |
| Non-Small Cell Lung Carcinoma | — | P2 | CCC · 53 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- Enfortumab Vedotin (Fully Human Monoclonal Antibody Conjugated To A Cytotoxic Agent Monomethyl Auristatin E (Mmae) Targeting Nectin-4)Fred Hutchinson Cancer CenterBB
- PembrolizumabFred Hutchinson Cancer CenterB
- AtezolizumabNational Cancer Institute (NCI)B
- ApsololEmory UniversityCCC
- Eribulin MonomethanesulfonateNational Cancer Institute (NCI)CCC
Citation
Floatz Terminal. Quemliclustat in Malignant Renal Pelvis Neoplasm. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/quemliclustat-malignant-renal-pelvis-neoplasm
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