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Retifanlimab

High Grade B-Cell Lymphoma

Explore 85 assets in High Grade B-Cell Lymphoma
Floatz Rating
CC47/100
Confidence
Indicative
v0.2
Sponsor
University of Washington
Modality
monoclonal_antibody
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Tafasitamab, Retifanlimab, and Rituximab in Combination With Standard Therapy for the Treatment of Diffuse Large B-cell Lymphoma
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · High Grade B-Cell Lymphoma

AssetSponsorPhaseRating
Retifanlimab (this asset)University of WashingtonP1/2CC · 47
EtoposideUniversity of WashingtonP3BB
IsocyclophosphamideUniversity of California, DavisP3BB
Vincristine SulfateNational Cancer Institute (NCI)P2/3BB
AdriamycinNational Cancer Institute (NCI)P3BB
PrednisoneNational Cancer Institute (NCI)P3BB
Axicabtagene CiloleucelAIDS Malignancy ConsortiumP2BB
DexasoneUniversity of California, DavisP2BB
RituximabNational Cancer Institute (NCI)P3BB

+42 more in the High Grade B-Cell Lymphoma cohort

Other indications for Retifanlimab

IndicationSponsorPhaseRating
Anal Canal Squamous Cell CarcinomaP3BB · 66
Urothelial CarcinomaP2BB · 66
Renal Cell CarcinomaP2B · 63

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Retifanlimab in High Grade B-Cell Lymphoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/retifanlimab-high-grade-b-cell-lymphoma

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