Revumenib
Acute Leukemia Of Ambiguous Lineage
Explore 43 assets in Acute Leukemia Of Ambiguous Lineage →Floatz Rating
B59/100
Confidence
Indicative
Sponsor
SWOG Cancer Research Network
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
51Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07636564CT.gov Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More Treatment | — | Not Yet Recruiting | — | — | — |
NCT06575296CT.gov Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant | — | Recruiting | — | — | — |
NCT06177067CT.gov Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia | — | Recruiting | — | — | — |
NCT05761171CT.gov A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia | — | Active Not Recruiting | — | — | — |
NCT04065399CT.gov A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
73High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Acute Leukemia Of Ambiguous Lineage
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Revumenib (this asset) | SWOG Cancer Research Network | P2 | B · 59 |
| Cyclophosphamide | SWOG Cancer Research Network | P2 | BB |
| L-Ofloxacin | Children's Oncology Group | P3 | BB |
| Cytarabine | SWOG Cancer Research Network | P2 | B |
| Vincristine Sulfate | Children's Oncology Group | P2 | B |
| Fludarabine | Janssen Research & Development, LLC | P2 | B |
| Methotrexate | SWOG Cancer Research Network | P2 | B |
| Dexasone | SWOG Cancer Research Network | P2 | B |
| (+)-Vincristine | SWOG Cancer Research Network | P2 | B |
+42 more in the Acute Leukemia Of Ambiguous Lineage cohort
Other indications for Revumenib
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Acute Myeloid Leukemia | — | P3 | B · 63 |
| Acute Myeloid Leukemia, MLL Gene Rearrangement | — | P2 | B · 60 |
| Mixed Phenotype Acute Leukemia | — | P2 | B · 59 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Revumenib in Acute Leukemia Of Ambiguous Lineage. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/revumenib-acute-leukemia-of-ambiguous-lineage
Are you the sponsor?
Submit your data room for a Verified Rating. The public-data rating remains visible alongside.
Contact →