Ribociclib
Uterine Corpus Endometrial Carcinoma
Explore 13 assets in Uterine Corpus Endometrial Carcinoma →Floatz Rating
B57/100
Confidence
Indicative
Sponsor
Mayo Clinic
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
42Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02657928CT.gov Ribociclib and Letrozole in Treating Patients With Relapsed ER Positive Ovarian, Fallopian Tube, Primary Peritoneal, or Endometrial Cancer | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Uterine Corpus Endometrial Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Ribociclib (this asset) | Mayo Clinic | P2 | B · 57 |
| Temsirolimus | National Cancer Institute (NCI) | P2 | B |
| Letrozole | Mayo Clinic | P2 | B |
| Mirvetuximab Soravtansine | Ohio State University Comprehensive Cancer Center | P1 | CCC |
| Cyclophosphamide | Mayo Clinic | P1/2 | CCC |
| Pembrolizumab | Mayo Clinic | P1/2 | CCC |
| Sargramostim | Mayo Clinic | P1/2 | CCC |
| Dasatinib | National Cancer Institute (NCI) | P1 | CC |
| Rucaparib | Ohio State University Comprehensive Cancer Center | P1 | CC |
+14 more in the Uterine Corpus Endometrial Carcinoma cohort
Other indications for Ribociclib
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Hormone Receptor-Positive Breast Cancer | — | P4 | BBB · 73 |
| Breast Cancer | — | P4 | BB · 70 |
| Estrogen-Receptor Positive Breast Cancer | — | P3 | BB · 69 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Ribociclib in Uterine Corpus Endometrial Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ribociclib-uterine-corpus-endometrial-carcinoma
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