Floatz Rating
BB64/100
Confidence
Indicative
Sponsor
Population Health Research Institute
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
52Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07468448CT.gov Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in IntraCranial Atherosclerotic diseaSe (CATIS- ICAS) | — | Not Yet Recruiting | — | — | — |
NCT05700266CT.gov Anticoagulation Using Rivaroxaban on Top of Aspirin in Intracranial Atherosclerotic Stenosis | — | Unknown | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Cerebral Atherosclerosis
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Rivaroxaban (this asset) | Population Health Research Institute | P3 | BB · 64 |
| Ferumoxytol | Northwestern University | P4 | BB |
| Atorvastatin | General Hospital of Shenyang Military Region | P4 | BB |
| Probucol | General Hospital of Shenyang Military Region | P4 | BB |
| Rucacuzumab | Peking Union Medical College Hospital | P4 | BB |
| Rosuvastatin | Samsung Medical Center | P4 | BB |
| Immunoglobulin G1 (256-Tyrosine,258-Threonine,260-Glutamic Acid), Anti-(Neural Apoptosis-Regulated Proteinase 1) (Human-Mus Musculus Monoclonal Hrp00130 .Gamma.1-Chain), Disulfide With (3-Valine,5-Serine,49-Serine,66-Aspartic Acid) Human-Mus Musculus Monoclonal Hrp00130 .Kappa.-Chain, Dimer | Peking Union Medical College Hospital | P4 | BB |
| Aspirin | Population Health Research Institute | P3 | BB |
| Alirocumab | Chang Gung Memorial Hospital | P2 | B |
+4 more in the Cerebral Atherosclerosis cohort
Other indications for Rivaroxaban
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Atrial Fibrillation | — | P4 | BBB · 79 |
| Hemorrhagic Disease | — | P4 | BBB · 76 |
| Thrombotic Disease | — | P4 | BBB · 76 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Rivaroxaban in Cerebral Atherosclerosis. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/rivaroxaban-cerebral-atherosclerosis
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