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Floatz Rating
CCC50/100
Confidence
Indicative
v0.2
Sponsor
Hoffmann-La Roche
Modality
UNKNOWN
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
45Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants With Obesity or Overweight
Recruiting
A Study Evaluating the Effect of Daily Oral RO7795081 in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity
Active Not Recruiting
A Study Investigating the Safety of RO7795081 and the Effect of RO7795081 on How the Body Processes Pitavastatin and Rosuvastatin in Otherwise Healthy Overweight or Obese Adult Participants
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
59High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Obesity Disorder

AssetSponsorPhaseRating
ro7795081 (this asset)Hoffmann-La RocheP2CCC · 50
vi-0521VIVUS LLCP4BBB
TirzepatideRoyal North Shore HospitalP4BBB
asc30Ascletis Pharma (China) Co., LimitedP2BBB
PhentermineRussell McCulloh, MDP4BBB
SurvodutideBoehringer IngelheimP3BBB
Deoxycholic AcidUniversity of California, San DiegoP4BBB
Efsubaglutide AlfaThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolP4BBB
CagrilintideNovo Nordisk A/SP3BBB

+42 more in the Obesity Disorder cohort

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. ro7795081 in Obesity Disorder. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/ro7795081-obesity-disorder

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