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Romidepsin

Hematopoietic And Lymphoid Cell Neoplasm

Explore 115 assets in Hematopoietic And Lymphoid Cell Neoplasm
Floatz Rating
CCC55/100
Confidence
Indicative
v0.2
Sponsor
Masonic Cancer Center, University of Minnesota
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
44High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies
Recruiting
CD34+ Enriched Transplants From HLA-Compatible Patients With Hematologic Malignancies
Withdrawn
Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant
Active Not Recruiting
Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction
Completed
Influence of Ketoconazole on the Pharmacokinetics of Romidepsin in Patients With Advanced Cancer
Completed
Influence of Rifampin on the Pharmacokinetics of Romidepsin in Patients With Advanced Cancer
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
73High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Hematopoietic And Lymphoid Cell Neoplasm

AssetSponsorPhaseRating
Romidepsin (this asset)Masonic Cancer Center, University of MinnesotaP2CCC · 55
NivestimSt. Jude Children's Research HospitalP2BB
PegloticaseM.D. Anderson Cancer CenterP4BB
RasburicaseM.D. Anderson Cancer CenterP4BB
PrednisoneM.D. Anderson Cancer CenterP2BB
Cyclosporin AChildren's Oncology GroupP3BB
HydromorphonM.D. Anderson Cancer CenterP4BB
NivolumabM.D. Anderson Cancer CenterP2BB
TacrolimusFred Hutchinson Cancer CenterP2BB

+42 more in the Hematopoietic And Lymphoid Cell Neoplasm cohort

Other indications for Romidepsin

IndicationSponsorPhaseRating
Burkitt LymphomaP2BBB · 73
Follicular LymphomaP2BBB · 73
Peripheral T-Cell Lymphoma, Not Otherwise SpecifiedP3BBB · 72

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Romidepsin in Hematopoietic And Lymphoid Cell Neoplasm. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/romidepsin-hematopoietic-and-lymphoid-cell-neoplasm

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