Romidepsin
Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma
Explore 19 assets in Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma →Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
National Cancer Institute (NCI)
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04639843CT.gov Doxorubicin, CC-(486) (5-azacitidine), Romidepsin, and Duvelisib (hARD) for T-cell Lymphoma | — | Withdrawn | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Romidepsin (this asset) | National Cancer Institute (NCI) | P1 | CC · 43 |
| Cyclophosphamide | National Cancer Institute (NCI) | P2 | BB |
| Adriamycin | Eric Jacobsen, MD | P2 | B |
| Azacitidine | National Cancer Institute (NCI) | P2 | B |
| Duvelisib | National Cancer Institute (NCI) | P2 | CCC |
| Cerdulatinib | Portola Pharmaceuticals | P2/3 | CCC |
| Prednisone | Eric Jacobsen, MD | P2 | CCC |
| Camustine | Eric Jacobsen, MD | P2 | CCC |
| Cytarabine | Eric Jacobsen, MD | P2 | CCC |
+11 more in the Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma cohort
Other indications for Romidepsin
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Burkitt Lymphoma | — | P2 | BBB · 73 |
| Follicular Lymphoma | — | P2 | BBB · 73 |
| Peripheral T-Cell Lymphoma, Not Otherwise Specified | — | P3 | BBB · 72 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Romidepsin in Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/romidepsin-monomorphic-epitheliotropic-intestinal-t-cell-lymphoma
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