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Ruxolitinib Phosphate

Myelodysplastic/Myeloproliferative Neoplasm

Explore 42 assets in Myelodysplastic/Myeloproliferative Neoplasm
Floatz Rating
B59/100
Confidence
Indicative
v0.2
Sponsor
M.D. Anderson Cancer Center
Modality
UNKNOWN
Development Phase
Phase 1/2
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
49High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Ruxolitinib Phosphate and Decitabine in Treating Patients With Relapsed or Refractory or Post Myeloproliferative Acute Myeloid Leukemia
Completed
INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative Disease
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Myelodysplastic/Myeloproliferative Neoplasm

AssetSponsorPhaseRating
Ruxolitinib Phosphate (this asset)M.D. Anderson Cancer CenterP1/2B · 59
EtoposideM.D. Anderson Cancer CenterP3BBB
Cyclosporin AMemorial Sloan Kettering Cancer CenterP3BBB
MelphalanM.D. Anderson Cancer CenterP2/3BBB
CytarabineFred Hutchinson Cancer CenterP3BBB
BusulfanumJacqueline Garcia, MDP2/3BBB
Anti-Human T-Lymphocyte Immunoglobulin, RabbitM.D. Anderson Cancer CenterP2/3BBB
FludarabineFred Hutchinson Cancer CenterP3BBB
TacrolimusM.D. Anderson Cancer CenterP2BBB

+42 more in the Myelodysplastic/Myeloproliferative Neoplasm cohort

Other indications for Ruxolitinib Phosphate

IndicationSponsorPhaseRating
Mature T-Cell And NK-Cell Non-Hodgkin LymphomaP2BB · 64
Acute Myeloid LeukemiaP2B · 56
Myelodysplastic SyndromeP2CCC · 55

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Ruxolitinib Phosphate in Myelodysplastic/Myeloproliferative Neoplasm. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/ruxolitinib-phosphate-myelodysplasticmyeloproliferative-neoplasm

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