Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Akira Sekikawa
Modality
UNKNOWN
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05741060CT.gov Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Arteriosclerosis Disorder
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| S-Equol (this asset) | Akira Sekikawa | P2 | CCC · 53 |
| Dapagliflozin | University Medical Centre Ljubljana | P4 | BBB |
| Glibenclamide | University of Campinas, Brazil | P4 | BB |
| Aspirin | Yonsei University | P4 | BB |
| Dipyridamole | UMC Utrecht | P4 | BB |
| Ranolazine | East Carolina University | P4 | BB |
| Apixaban | Yonsei University | P4 | BB |
| Clopidogrel | Yonsei University | P4 | BB |
| Rimonabant | Sanofi | P3 | CC |
+2 more in the Arteriosclerosis Disorder cohort
Other indications for S-Equol
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Alzheimer Disease | — | P1/2 | CCC · 53 |
| Cognitive Disorder | — | P2 | CCC · 53 |
| Breast Cancer | — | Early P1 | C · 36 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. S-Equol in Arteriosclerosis Disorder. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/s-equol-arteriosclerosis-disorder
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