S230815
Developmental And Epileptic Encephalopathy
Explore 7 assets in Developmental And Epileptic Encephalopathy →Floatz Rating
CCC48/100
Confidence
Indicative
Sponsor
Institut de Recherches Internationales Servier
Modality
UNKNOWN
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07227857CT.gov A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Developmental And Epileptic Encephalopathy
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| S230815 (this asset) | Institut de Recherches Internationales Servier | P1/2 | CCC · 48 |
| Bexicaserin | Longboard Pharmaceuticals | P3 | BB |
| Benzeneethanamine, N-Ethyl-?-Methyl-4-(Trifluoromethyl)-, Hydrochloride, (±)- | Zogenix, Inc. | P3 | BB |
| Elsunersen | Praxis Precision Medicines | P3 | B |
| Nbi-827104 | Neurocrine Biosciences | P2 | CCC |
| Melatonin | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | P2 | CCC |
| Soticlestat | Takeda | P1/2 | CCC |
| Stiripentol | Biocodex | P1 | CC |
| Cannimed® 1:20 | University of Saskatchewan | P1 | CC |
+1 more in the Developmental And Epileptic Encephalopathy cohort
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. S230815 in Developmental And Epileptic Encephalopathy. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/s230815-developmental-and-epileptic-encephalopathy
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