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Floatz Rating
B63/100
Confidence
Indicative
v0.2
Sponsor
Uppsala University
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
65High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Volatile Anaesthesia and Perioperative Outcomes Related to Cancer: the VAPOR-C Trial
Terminated
Elucidation of the Mechanisms and Effects of Certain Anesthetic Interventions on Digestive Cancer Patients Subjected to Surgery
Unknown
Anesthesia, TIVA, Balanced Anesthesia, NK Cell
Withdrawn
Volatile Anaesthesia and Perioperative Outcomes Related to Cancer Feasibility Study
Completed
Anesthesia and Postoperative Outcome in Colorectal Cancer Patients
Unknown

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
59High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Colorectal Cancer

AssetSponsorPhaseRating
Sevoflurane (this asset)Uppsala UniversityApprovedB · 63
DesfluranePeter MacCallum Cancer Centre, AustraliaP4BBB
Marble DustJames VaraniP2/3BB
OxaliplatinChia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.P4BB
OrectalipSinphar Pharmaceutical Co., LtdP4BB
FluorouracilumUNICANCERP4BB
Levofolinic AcidSuzhou Suncadia Biopharmaceuticals Co., Ltd.P3BB
FentanylMansoura UniversityP4BB
PanitumumabMSPU des 3 ProvincesP3BB

+42 more in the Colorectal Cancer cohort

Other indications for Sevoflurane

IndicationSponsorPhaseRating
Prostate CancerP4BB · 68
CancerP4BB · 68
Lung CancerP4BB · 68

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Sevoflurane in Colorectal Cancer. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/sevoflurane-colorectal-cancer

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