Floatz Rating
CCC51/100
Confidence
Indicative
Sponsor
British Columbia Cancer Agency
Modality
mixture
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
36High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT00573885CT.gov Green Tea Extract in Preventing Cancer in Former and Current Heavy Smokers With Abnormal Sputum | — | Completed | — | — | — |
NCT00611650CT.gov Green Tea Extract in Treating Current or Former Smokers With Bronchial Dysplasia | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Nicotine Dependence
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Sinecatechins (this asset) | British Columbia Cancer Agency | P2 | CCC · 51 |
| Nicotine | Brown University | P4 | A |
| Varenicline | University of California, San Diego | P4 | A |
| Naltrexone | Yale University | P4 | BBB |
| Semaglutide | University of Oklahoma | P4 | BBB |
| Minocycline | University of Maryland, Baltimore | P4 | BB |
| Cephalexin | Mayo Clinic | P4 | BB |
| Cefadroxil Anhydrous | Mayo Clinic | P4 | BB |
| Dextrose | Butler Hospital | P3 | BB |
+18 more in the Nicotine Dependence cohort
Other indications for Sinecatechins
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Benign Prostatic Hyperplasia | — | P2 | CCC · 51 |
| Colorectal Adenoma | — | P2 | CCC · 48 |
| Prostate Carcinoma | — | P2 | CCC · 48 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Sinecatechins in Nicotine Dependence. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/sinecatechins-nicotine-dependence
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