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Floatz Rating
CC46/100
Confidence
Indicative
v0.2
Sponsor
Xiang Zhang
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
34Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Sitravatinib in Metastatic Breast Cancer
Terminated

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Breast Neoplasm

AssetSponsorPhaseRating
Sitravatinib (this asset)Xiang ZhangP2CC · 46
LetrozoleFujian Cancer HospitalP4BB
AdriamycinMerck Sharp & Dohme LLCP4BB
ExemestaneFujian Cancer HospitalP4BB
TamoxifenEli Lilly and CompanyP3BB
DocetaxelUniversitas AirlanggaP4BB
CyclophosphamideMerck Sharp & Dohme LLCP4BB
Microporous Polysaccharide HemospheresFundación para la Investigación del Hospital Clínico de ValenciaP4BB
EpirubicinUniversitas AirlanggaP4BB

+42 more in the Breast Neoplasm cohort

Other indications for Sitravatinib

IndicationSponsorPhaseRating
Nonpapillary Renal Cell CarcinomaP2B · 57
Renal Cell CarcinomaP2CCC · 55
Metastatic Malignant NeoplasmP2/3CCC · 54

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Sitravatinib in Breast Neoplasm. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/sitravatinib-breast-neoplasm

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