Floatz Rating
CC47/100
Confidence
Indicative
Sponsor
Sangamo Therapeutics
Modality
UNKNOWN
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06980948CT.gov Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN) | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Neuropathy, Painful
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| st-503 (this asset) | Sangamo Therapeutics | P1/2 | CC · 47 |
| Pregabalin | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | P4 | BB |
| Celecoxib | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | P4 | BB |
| Nepenthe | Nova Scotia Health Authority | P4 | BB |
| Naltrexone | Emory University | P4 | BB |
| Fentanyl | Cephalon | P3 | B |
| Lacosamide | Danish Pain Research Center | P2 | B |
| Incobotulinumtoxina | Merz Therapeutics GmbH | P2 | B |
| Valproic Acid | University Hospital, Bordeaux | P2/3 | CCC |
+11 more in the Neuropathy, Painful cohort
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. st-503 in Neuropathy, Painful. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/st-503-neuropathy-painful
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