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Stenoparib

Indolent B-Cell Non-Hodgkin Lymphoma

Explore 38 assets in Indolent B-Cell Non-Hodgkin Lymphoma
Floatz Rating
CCC52/100
Confidence
Indicative
v0.2
Sponsor
Eisai Limited
Modality
Small molecule
Development Phase
Phase 1/2
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
37Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
An Open-Label, Multicenter, Phase 1/2 Study of Poly(ADP-Ribose) Polymerase (PARP) Inhibitor E7449 as Single Agent in Subjects With Advanced Solid Tumors or With B-cell Malignancies and in Combination With Temozolomide (TMZ) or With Carboplatin and Paclitaxel in Subjects With Advanced Solid Tumors
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Indolent B-Cell Non-Hodgkin Lymphoma

AssetSponsorPhaseRating
Stenoparib (this asset)Eisai LimitedP1/2CCC · 52
CyclophosphamideInstitute of Hematology & Blood Diseases Hospital, ChinaP2BB
FludarabineInstitute of Hematology & Blood Diseases Hospital, ChinaP3BB
PembrolizumabUniversity of WashingtonP2BB
RituximabFox Chase Cancer CenterP3BB
Vaccin Genhevac B PasteurCentral Hospital, Nancy, FranceP4BB
IbrutinibSidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityP3BB
Cyclosporin AFred Hutchinson Cancer CenterP3BB
Polatuzumab VedotinUniversity of WashingtonP2BB

+42 more in the Indolent B-Cell Non-Hodgkin Lymphoma cohort

Other indications for Stenoparib

IndicationSponsorPhaseRating
Ovarian CancerP2BB · 64
Breast CancerP2BB · 64
CancerP1/2CCC · 48

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Stenoparib in Indolent B-Cell Non-Hodgkin Lymphoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/stenoparib-indolent-b-cell-non-hodgkin-lymphoma

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