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Floatz Rating
CCC48/100
Confidence
Indicative
v0.2
Sponsor
National Cancer Institute (NCI)
Modality
Small molecule
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.

No trial-level evidence is linked to this axis yet.

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Oropharynx Squamous Cell Carcinoma

AssetSponsorPhaseRating
SX682 (this asset)National Cancer Institute (NCI)P1/2CCC · 48
CetuximabNational Cancer Institute (NCI)P1/2B
IrinotecanAIDS Malignancy ConsortiumP1/2B
e7 tcr-t cellsChristian HinrichsP2B
Cis-Diamminedichloroplatinum IiImmunityBio, Inc.P2CCC
Immunoglobulin G4, Anti-(Human Programmed Cell Death Protein 1) (Human Monoclonal Regn2810 Heavy Chain), Disulfide With Human Monoclonal Regn2810 .Kappa.-Chain, DimerRegeneron PharmaceuticalsP2CCC
NivolumabNational Cancer Institute (NCI)P2CCC
CabozantinibNational Cancer Institute (NCI)P2CCC
had5-hpv vaccineImmunityBio, Inc.P2CCC

+23 more in the Oropharynx Squamous Cell Carcinoma cohort

Other indications for SX682

IndicationSponsorPhaseRating
Metastatic Prostate CarcinomaP2B · 60
Lung CancerP2CCC · 53
Non-Small Cell Lung CarcinomaP2CCC · 53

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. SX682 in Oropharynx Squamous Cell Carcinoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 11, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/sx682-oropharynx-squamous-cell-carcinoma

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