Floatz Rating
CC44/100
Confidence
Indicative
Sponsor
Syros Pharmaceuticals
Modality
Small molecule
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04247126CT.gov A Study of SY 5609, a Selective CDK7 Inhibitor, in Advanced Solid Tumors | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Small Cell Lung Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| SY 5609 (this asset) | Syros Pharmaceuticals | P1 | CC · 44 |
| Benmelstobart | Yayi He | P4 | BBB |
| Cis-Diamminedichloroplatinum Ii | National Cancer Institute (NCI) | P4 | BBB |
| Etoposide | Sichuan University | P4 | BBB |
| Anti-Pd-L1 Monoclonal Antibody Shr-1316 | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | P3 | BB |
| Irinotecan | Sichuan University | P4 | BB |
| Nogitecan | AbbVie | P4 | BB |
| Carboplatin | University of Maryland, Baltimore | P4 | BB |
| Berzosertib | National Cancer Institute (NCI) | P2 | BB |
+42 more in the Small Cell Lung Carcinoma cohort
Other indications for SY 5609
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Cancer | — | P1 | C · 39 |
| Breast Cancer | — | P1 | C · 39 |
| Pancreatic Neoplasm | — | P1 | C · 39 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. SY 5609 in Small Cell Lung Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 14, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/sy-5609-small-cell-lung-carcinoma
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