Tacrolimus
Malignant Peripheral Nerve Sheath Tumor
Explore 15 assets in Malignant Peripheral Nerve Sheath Tumor →Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
M.D. Anderson Cancer Center
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04530487CT.gov Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Malignant Peripheral Nerve Sheath Tumor
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Tacrolimus (this asset) | M.D. Anderson Cancer Center | P2 | CCC · 53 |
| Cyclophosphamide | St. Jude Children's Research Hospital | P2 | B |
| Fludarabine | St. Jude Children's Research Hospital | P2 | B |
| Pembrolizumab | Seattle Children's Hospital | P1/2 | CCC |
| Nivolumab | National Cancer Institute (NCI) | P2 | CCC |
| Thiotepa | M.D. Anderson Cancer Center | P2 | CCC |
| Selinexor | Memorial Sloan Kettering Cancer Center | P2 | CCC |
| Telaglenastat | National Cancer Institute (NCI) | P2 | CCC |
| Etoposide | M.D. Anderson Cancer Center | P2 | CCC |
+13 more in the Malignant Peripheral Nerve Sheath Tumor cohort
Other indications for Tacrolimus
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Disease Related To Transplantation | — | P4 | BBB · 79 |
| Disease Related To Solid Organ Transplantation | — | P4 | BBB · 76 |
| Beta-Thalassemia Major | — | P4 | BBB · 75 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Tacrolimus in Malignant Peripheral Nerve Sheath Tumor. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/tacrolimus-malignant-peripheral-nerve-sheath-tumor
Are you the sponsor?
Submit your data room for a Verified Rating. The public-data rating remains visible alongside.
Contact →