Floatz Rating
CCC49/100
Confidence
Indicative
Sponsor
M.D. Anderson Cancer Center
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
39High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03968406CT.gov Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers | — | Recruiting | — | — | — |
NCT02627430CT.gov Talazoparib and HSP90 Inhibitor AT13387 in Treating Patients With Metastatic Advanced Solid Tumor or Recurrent Ovarian, Fallopian Tube, Primary Peritoneal, or Triple Negative Breast Cancer | — | Withdrawn | — | — | — |
NCT02316834CT.gov Talazoparib in Determining Genetic Effects on Disease Response in Patients With Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cancer | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Fallopian Tube Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Talazoparib (this asset) | M.D. Anderson Cancer Center | P1 | CCC · 49 |
| Carboplatin | Women's Hospital School Of Medicine Zhejiang University | P3 | BBB |
| Cis-Diamminedichloroplatinum Ii | Mayo Clinic | P3 | BB |
| Pembrolizumab | Roswell Park Cancer Institute | P2 | BB |
| Cyclophosphamide | Mayo Clinic | P2 | BB |
| Tamoxifen | Nordic Society of Gynaecological Oncology - Clinical Trials Unit | P3 | BB |
| Olaparib | National Cancer Institute (NCI) | P3 | BB |
| Guadecitabine | National Cancer Institute (NCI) | P2 | BB |
| Adriamycin | Brigham and Women's Hospital | P3 | BB |
+42 more in the Fallopian Tube Carcinoma cohort
Other indications for Talazoparib
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| BRCA2-Related Cancer Predisposition | — | P3 | BB · 68 |
| Castration-Resistant Prostate Carcinoma | — | P2 | BB · 65 |
| Her2-Receptor Negative Breast Cancer | — | P2 | BB · 64 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Talazoparib in Fallopian Tube Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/talazoparib-fallopian-tube-carcinoma
Are you the sponsor?
Submit your data room for a Verified Rating. The public-data rating remains visible alongside.
Contact →