Tarlatamab
Pulmonary Large Cell Neuroendocrine Carcinoma
Explore 8 assets in Pulmonary Large Cell Neuroendocrine Carcinoma →Floatz Rating
CC47/100
Confidence
Indicative
Sponsor
University of Arizona
Modality
monoclonal_antibody
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06814496CT.gov Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Pulmonary Large Cell Neuroendocrine Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Tarlatamab (this asset) | University of Arizona | P1/2 | CC · 47 |
| Abemaciclib | Case Comprehensive Cancer Center | P2 | B |
| Pembrolizumab | Ochsner Health System | P2 | CCC |
| 68Ga-NOTA-AE105 | Rigshospitalet, Denmark | P2 | CCC |
| [203Pb]Pb-MP0712 | Molecular Partners AG | P1/2 | CCC |
| [212pb]pb-mp0712 | Molecular Partners AG | P1/2 | CCC |
| lb2102 | Legend Biotech USA Inc | P1 | CC |
| 225ac-abd147 | Abdera Therapeutics Inc. | P1 | CC |
| 111in-etn029 | Novartis Pharmaceuticals | P1 | CC |
+2 more in the Pulmonary Large Cell Neuroendocrine Carcinoma cohort
Other indications for Tarlatamab
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Small Cell Lung Carcinoma | — | P3 | BB · 65 |
| Medullary Thyroid Gland Carcinoma | — | P2 | B · 60 |
| Neuroendocrine Carcinoma | — | P2 | B · 60 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Tarlatamab in Pulmonary Large Cell Neuroendocrine Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/tarlatamab-pulmonary-large-cell-neuroendocrine-carcinoma
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