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Floatz Rating
CC45/100
Confidence
Indicative
v0.2
Sponsor
University of Arizona
Modality
monoclonal_antibody
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Testicular Cancer

AssetSponsorPhaseRating
Tarlatamab (this asset)University of ArizonaP1/2CC · 45
Testosterone UndecylateUniversity Medical Center GroningenP2/3BB
FluorouracilumNational Cancer Institute (NCI)P2B
AlvocidibNational Cancer Institute (NCI)P2B
EtarfolatideEndocyteP2B
OxaliplatinNational Cancer Institute (NCI)P2CCC
DurvalumabLudwig Institute for Cancer ResearchP1/2CCC
Immunoglobulin G2, Anti-(Human Ctla-4 (Antigen)) (Human Monoclonal Cp-675206 Clone 11.2.1 Heavy Chain) Disulphide With Human Monoclonal Cp-675206 Clone 11.2.1 Light Chain, DimerLudwig Institute for Cancer ResearchP1/2CCC
GuadecitabineNasser HannaP1CC

+12 more in the Testicular Cancer cohort

Other indications for Tarlatamab

IndicationSponsorPhaseRating
Small Cell Lung CarcinomaP3BB · 65
Medullary Thyroid Gland CarcinomaP2B · 60
Neuroendocrine CarcinomaP2B · 60

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Tarlatamab in Testicular Cancer. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/tarlatamab-testicular-cancer

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